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https://discourse.soylent.com/t/nusi-metabolic-ward-study-on-low-carb-the-insulin-hypothesis/25432

NuSI metabolic ward study on low-carb & the insulin hypothesis
Nutrition


May 2 '16

So Gary Taubes’ organization, NuSI, helped fund a study by Dr. Yoni Feedhoff (which was also funded by the NIH).

They had 19 individuals on a carefully controlled diet, at a fixed calorie level, go through a baseline diet with normal carbs, and then a low-carb diet with 5% carbs for a month (in total, a 2-month study.) They had repeated 24-hour metabolic ward habitations during the study in order to watch their change in energy expenditure and their oxidation rates as they shifted from normal metabolism to ketosis. They measured fat levels with DXA.

Basically, this expensive study went with the gold standards for measurement accuracy on everything.

Most interesting (to me) findings:

During the 15 days on the “baseline” normal diet with carbs, the subjects were already losing fat - even though they were supposedly eating the same “normal” number of calories they ate previously! This is just another example of how people are nearly always eating more than they think; and when they’re forced to eat only how much they thought they were eating, they often lose weight and lose fat.

During the subsequent 30 days on the low-carb diet, the subjects lost only as much fat as they lost in the first 15 days. In other words, fat loss slower while eating low-carb, even though eating the exact same number of calories and getting the exact same amount of activity. (They did have a jolt of rapid non-fat weight loss at the beginning of the transition, as the body’s protein burning went up before the body could become adequately fat-adapted, but for the rest of the thirty days, fat loss was slower than while previously eating carbs.)

They conclude there’s no metabolic advantage to a low-carb diet, and that that the insulin hypothesis proves invalid as regards metabolism and fat storage / fat bruning. (But that there’s some interesting help on the appetite management side.)


The role of metabolic ward in nutritional studies

https://academic.oup.com/ajcn/article-abstract/24/8/930/4733175?redirectedFrom=PDF

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Комментария 
This one never gets old. Taubes' own organization funded a study that backfires. 
05 ноя 19 написано членом: -Diablo
He wanted to prove LC was superior. So it indeed backfired. He will keep selling his book of myth though. 
06 ноя 19 написано членом: -Diablo
It invalidates the insulin hypothesis. Something that Taubes still pushes to this day to sell more books. 
06 ноя 19 написано членом: -Diablo
Insulin hypothesis of obesity* 
06 ноя 19 написано членом: -Diablo
They did only study 19 people which is not statistically significant. I am all CICO myself but it's easy to talk yourself into whatever you want to have work. 
06 ноя 19 написано членом: abbadabba
Yeah it is significant or else they wouldn't have spent the money that they spent on it trying to prove a point, and I posted plenty of metabolic Ward studies involving hundreds of people so you choose to omit those or maybe you conveniently missed them over the several years I've been on here. 
06 ноя 19 написано членом: -Diablo
I used to do LCHF, lost weight, now I do HCLF, lost weight. Trying to avoid HCHF. But, perhaps, "lost weight" is more from a constant cal deficit and less from Macros. 
06 ноя 19 написано членом: rgaDawg
I lost on high fat high carb low protein. At the time I didn't know it, but the lack of protein caused more muscle loss than was necessary. Now, since I lost via low fat, high fat, and high protein my muscle retention and strength levels are much better. 
06 ноя 19 написано членом: -Diablo
Yes, different people need to experiment with what keeps their hunger at bay. Other than that, there is no difference in fat loss as long as protein and calories are equal. 
06 ноя 19 написано членом: -Diablo
Yeah I shouldn't even be awake yet, I meant high carb high protein. 
06 ноя 19 написано членом: -Diablo

     
 

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